After being swept by the Celtics (2) in the regular season, can the Knicks (3) push the reigning champs in a series that oddsmakers do not expect to be competitive?The Celtics are coming off a 4-1 win over the Magic (7) in the first round, while the Knicks needed six games to take down the young, scrappy Pistons (6).We last night in Cleveland that heavy favorites in the conference semifinals of the NBA playoffs are no sure thing, as the Pacers (4) beat the Cavs (1) 121-112 as 3-to-1 underdogs on the moneyline.Knicks vs. Celtics Series Winner Odds DraftKings: NYK +550; BOS -800 FanDuel: NYK +590; DET -850 Knicks vs. Celtics Game 1 Betting Odds 213.5 (o-110; u-110) 213 (o-112; u-108) 213 (o-110; u-110) How to Watch Knicks vs. Celtics Game 1 Tipoff: 7 p.m. ET Channel: TNT/truTV/Max Knicks vs. Celtics Game 1 Player PropsJayson Tatum 30+ Points (+145 at bet365) -- 1 unitSometimes, an obvious pick like a superstar against a team without an apparent answer for him is the way to go.If the four regular-season matchups between these teams are anything to go by, Tatum vs. the Knicks tonight is a great example of that. He averaged 33.5 points per game vs. New York, including a 37-point night in just 30 minutes in the season opener back in October.On paper, the Knicks have two solid wings to throw at Tatum in Mikal Bridges and OG Anunoby. Neither had much success slowing him down in the regular season, though.Tatum is also coming into tonight's game having torched the Magic for 36, 37 and 35 points in Games 3, 4 and 5 of that series on a combined 30-for-63 shooting from the floor (11-for-25 3PT).After a grueling, six-game series against the Pistons in which one game after another came down to the final minutes, don't be surprised if the Knicks (once again) struggle to contain Tatum, who alsoKnicks vs. Celtics Game 1 Injury NewsBoth these teams enter tonight's game with no players listed on the injury report. That's significant news for the Celtics, who were without starting point guard Jrue Holiday (hamstring) for Games 3, 4 and 5 of their first-round series against Orlando -- and also had to win Game 2 vs. the Magic without Jayson Tatum (wrist).Knicks vs. Celtics Game 1 Pick, Best BetsThis series strikes me as the biggest mismatch of the second round, especially if Knicks coach Tom Thibodeau insists on playing his starters 40-plus minutes per night.I expect a big night from Boston in its first game with its starting five of Holiday, Tatum, Jaylen Brown, Derrick White and Kristaps Porzingis since Game 1 of the first round.With their entire rotation healthy -- and coming off a break that dates back to last Tuesday -- the Celtics should win this game comfortably if they're firing on all cylinders.Between Jalen Brunson and Karl-Anthony Towns, the Knicks have the firepower to keep this game close for a while. Still, I like the Celtics to cover the substantial spread in this game, and I also like the C's -- who scored at least 118 points every time these rivals met in the regular season -- to go over their team total tonight.Knicks vs. Celtics Game 1 Best Bets: Celtics -9 (-110 at DraftKings) -- 1 unit Celtics Team Total Over 111.5 (-108 at FanDuel) -- 1 unit Newsweek may earn an affiliate commission if you sign up through the links in this article. See the sportsbook operator's terms and conditions for important details. Sports betting operators have no influence over newsroom coverage.