In the Midwest Region, No. 4 seed Purdue takes on No. 12 seed McNeese for a spot in the Sweet 16. The Cowboys have already scored one major upset in this tournament, knocking off Clemson in the first round. Can they make it two upsets?Will it be McNeese or Purdue that advances? Tune in to CBS to find out.How to Watch McNeese vs Purdue: Date: Saturday, Mar. 22, 2025 Time: 12:00 PM EDT Channel: CBS Stream: Fubo (Try for free) McNeese defeated Clemson 69-67 on Thursday. Brandon Murray came off the bench to score a team-high 21 points on 10-for-18 shooting to help lead the Cowboys to the upset victory. Christian Shumate had a double-double with 13 points and 11 rebounds.Purdue took down High Point 75-63. HPU had been a trendy upset pick, but Trey Kaufman-Renn scored 21 points and grabbed eight boards to help the Boilermakers avoid the upset loss and move on to the second round. Braden Smith added 20 points for Purdue and dished out six assists in the win.Who will win this game on Saturday? Tune in to CBS at 12:00 PM EDT to see if McNeese or Purdue advances. Start your free trial of Fubo now to get started watching.Live stream the NCAA Men's Tournament - Second Round: McNeese vs Purdue game on Fubo: Start your free trial now!Regional restrictions may apply. If you purchase a product or register for an account through one of the links on our site, we may receive compensation.