Bath finished 11 points clear at the top of the table this season and go into Saturday as heavy favourites, having also beaten Leicester comprehensively 43-15 when the two sides met just four weeks ago.
The Somerset side are in line to win a historic treble if they clinch the Premiership title, having also won the Premiership Rugby Cup and European Challenge Cup this season.
Fittingly, however, the only other English side to win a treble is Leicester in 2001 when they won the league, the inaugural Zurich Championship and the Heineken Cup.
Yet 1996 was the last time Bath were crowned English champions, 29 years ago. And while they were beaten in the 2015 final by Saracens and fell narrowly short against Northampton last season, just three seasons ago they finished rock bottom of the table.
Leicester head coach Michael Cheika has conceded his side are underdogs but still have plenty of "belief".
They were last crowned champions just three years ago in 2022.
The Australian, who will take charge of his final Tigers match, said the club's successful history alone will not be enough.
"To tap into that [history] alone won't be enough to beat those fellas," said Cheika. "For all I know they are tapping into it as well. Who knows?
"I love the history but we have got to play in the way we are playing now and think about the things that we are dealing with right now and use that."
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