Southwest Airlines will launch a new nonstop flight from Indianapolis International Airport to San Jose del Cabo’s Los Cabos International Airport starting for Spring Break 2026. This will be the first direct flight from Indianapolis to Cabo, WTHR reported. Currently, Southwest and American Airlines offer nonstop flights to Cancun, and Delta Air Lines plans to begin nonstop service to Cancun in December 2025. WRTV also reported that new routes to cities such as Chicago Midway, Nashville, and Portland have been added in 2025. The new nonstop flight to Cabo adds to the growing list of direct routes from Indianapolis International Airport, providing travelers with additional destination options.