USA takes on Costa Rica tonight in the Gold Cup quarterfinals in one of the biggest games of Manager Mauricio Pochettino's stint at the helm of the USMNT.Though the team is currently without a number of its best players, including stars Christian Pulisic and Weston McKennie, a loss to this Costa Rica squad would mark a massive disappointment just one year after a full-strength lineup failed to reach the knockout stage of the 2024 Copa America.Following a pair of disastrous showings in pre-Gold Cup friendlies vs. Turkey and Switzerland -- which the American lost by a combined score of 6-1 -- they took down Trinidad and Tobago, Saudi Arabia and Haiti in group play to reach the quarters.Costa Rica, which has traditionally been a tough opponent for the United States, is coming off a solid showing in group play. Los Ticos beat Suriname and the Dominican Republic and also earned a 0-0 draw against tournament favorite Mexico.USA vs. Costa Rica Betting OddsBelow are the odds from three top sportsbooks in the two most popular markets for soccer matches: three-way moneyline and match winner.Gold Cup Quarterfinal Moneyline Odds: USA vs. Costa RicaThe DraftKings, FanDuel and bet365 three-way moneyline odds below apply to today's result after 90 minutes, plus stoppage time. Gold Cup Quarterfinal Winner Odds: USA vs. Costa RicaSportsbooks also offer each team's odds to advance tonight.In this market, it doesn't matter whether the winner comes out on top in 90 minutes, extras or PKs. How to Watch USA vs. Costa Rica Gold Cup Quarterfinals Kickoff: 7 p.m. ET TV: FOX/Universo USA vs. Costa Rica Betting AnalysisThe odds for tonight's game give Costa Rica very little respect, and they also downplay how uninspiring (or worse) the Americans have looked under Mauricio Pochettino in 2025.And remember, the USMNT lost to Costa Rica in both qualifiers ahead of the 2018 World Cup, and it split its two 2022 World Cup qualifiers against Costa Rica.USA did, however, beat Costa Rica 3-0 in the most recent meeting between these teams in a friendly back in January.One big reason why the USA is so heavily favored tonight is that Costa Rica will be without two key starters in defender Joseph Mora and forward Manfred Ugalde. Ugalde is Costa Rica's top player, and he scored two goals vs. Suriname in group play, then tallied a goal and an assist vs. the Dominican Rebublic.Even shorthanded -- the only two starters from the 2022 World Cup who are starting for this squad are center back Tim Ream and midfielder Tyler Adams -- the USA has a talent advantage in this match, especially with Ugalde and Mora unavailable.But we've seen little reason to expect USA (FIFA No. 16) to win comfortably, as the Gold Cup group stage wins over Trinidad and Tobago (FIFA No. 100), Saudi Arabia (FIFA No. 58) and Haiti (FIFA No. 83) were just a case of the Americans handling overmatched opponents.Against a Costa Rica side (FIFA No. 54) that has not been great defensively, I expect a back-and-forth battle tonight, with the USA squeaking out a win.It would be a gross understatement to say that going out in the quarterfinals of the Gold Cup -- especially after entering this tournament on a four-game losing streak -- would ramp up doubts about USA's chances of making noise in the 2026 World Cup.I expect this to be a struggle for the USMNT early on, which makes the halftime draw tempting. The other play I'd recommend tonight is USA to Win and Over 1.5.USA vs. Costa Rica Best Bets Halftime draw (+115 at DK) -- 1 unit Parlay: USA To Win, Over 1.5 (+100 at DK) -- 1 unit Newsweek may earn an affiliate commission if you sign up through the links in this article. See the sportsbook operator's terms and conditions for important details. Sports betting operators have no influence over newsroom coverage.