A Mexican drug kingpin who was depicted in Netflix’s gritty crime drama “Narcos” was arraigned Friday in Brooklyn — wearing the handcuffs that belonged to the DEA agent he was convicted of kidnapping, torturing and murdering in 1985. Rafael Caro Quintero, a founding member of the Guadalajara cartel, was arraigned on drug trafficking charges in federal court. He pleaded not guilty in front of a room of more than 100 Drug Enforcement Administration agents and other members of law enforcement. The white-haired Quintero, 72, who wore tan pants and a blue and orange shirt, was brought into the courtroom with his hands cuffed behind his back and answered questions in Spanish. A source confirmed to The Post that the cuffs he wore previously belonged to DEA agent Enrique “Kiki” Camarena, whose kidnapping, torture and murder Caro Quintero was convicted for. Caro Quintero’s men abducted Camarena and tortured and interrogated him for approximately two days, after which Caro Quintero and his men killed Camarena, officials said. Camarena’s son, Enrique Camarena, who is a judge in the San Diego area, posed in a photo with DEA Agent Steve Paris, who was proudly holding the iconic cuffs before they were used to arrest Caro Quintero. Caro Quintero spent 28 years in prison in Mexico for orchestrating Camarena’s death, a scene that was dramatized in the first season of the series “Narcos: Mexico.” He continued operating his drug trafficking organization from behind bars with the help of family members and associates on the outside, according to prosecutors. Caro Quintero was known as the “Narco of Narcos,” and founded one of the largest drug organizations in the world, US Attorney John J. Durham said at a press conference Friday. Caro Quintero and his partners pioneered drug-trafficking routes through Columbia, Mexico, and into the US to “build one of the largest drug organizations in the world.” “Having built this lucrative business, Caro Quintero used extreme violence to protect the cartel’s operations, beating and killing anyone who got in his way,” Durham said. The violent organization trafficked heroin, methamphetamine, cocaine and marijuana, and partnered with the Sinaloa cartel to shuttle four tons of drugs that were season in New York, Durham said. Caro Quintero, previously among the FBI’s most wanted fugitives, was among 29 cartel members released into US custody by the Mexican government Thursday. Durham called the arrival of Caro Quintero at JFK airport Thursday a “historic moment.” “It demonstrated the tenacity of countless members of the criminal justice system who work hard and risk their lives to protect our communities from drug traffickers regardless of where they are from,” he said. “But most importantly, it demonstrated you can never kill a DEA agent, and you will never get away with it,” Durham added. Caro Quintero faces a mandatory life sentence or possibly the death penalty if convicted. He was charged with leading a criminal enterprise, international narcotics distribution and unlawful use of firearms in drug trafficking. Quintero being transferred to US custody was personal for DEA agents, even bigger than the capture of Joaquin “El Chapo” Guzman. Guzmán was arraigned in January 2017, also in Brooklyn Federal Court, after being extradited to the US from Mexico. “This was personal,” Ray Donovan, the former head of New York’s DEA office, preciously told The Post. Though Caro Quintero’s charges don’t include murder, Donovan said he believes the kingpin’s role in Camarena’s murder will be revealed during the trial. “They are no longer just criminals,” Donovan also said. “They are terrorists.” President Trump ordered the cartel members be designated as terrorists, which sped up their extradition. Previous requests to the Mexican government by the Biden administration were not honored, according to the US Department of Justice. “The Trump Administration is declaring these thugs as terrorists, because that is what they are, and demanding justice for the American people,” White House press secretary Karoline Leavitt said in a statement. She slammed the previous administration for allowing the criminals to “run free and commit crimes all over the world” and credited Attorney General Pam Bondi and Secretary of State Marco Rubio for doing a “tremendous job” in getting the extraditions done. Vicente Castillo Fuentes of the Juarez Cartel was also arraigned Friday, and also pleaded not guilty. “This is a significant case and a dangerous criminal,” US Attorney Erik Paulsen said at the hearing. Paulsen argues that Fuentes was “directly responsible” for actions taken by the drug cartel that he “led for nearly 20 years.” “He is dangerous of extraordinary violence left in his wake,” he added. Fuentes and Caro Quintero are both due back in court at the end of March, according to the US Attorney’s Office.