"Our goal is to deploy the Rhisotope technology at scale to help protect one of Africa's most iconic and threatened species," said Jessica Babich, head of the Rhisotope Project.
"By doing so, we safeguard not just rhinos but a vital part of our natural heritage."
Tests conducted in the pilot study, which involved 20 rhinos, confirmed that the radioactive material was not harmful to the animals.
"We have demonstrated, beyond scientific doubt, that the process is completely safe for the animal and effective in making the horn detectable through international customs nuclear security systems," said James Larkin a professor at Wits University who is also part of the project.
The Wits University researchers, who collaborated with the International Atomic Energy Agency, found horns could even be detected inside full 40-foot (six-metre) shipping containers.
Each year since 2021, more than 400 rhinos have been poached in South Africa, says conservation charity Save the Rhino.
The horns of African rhinos are often exported to Asian markets were they are used in traditional medicine and also seen as a status symbol.
White rhinos are considered threatened, while black rhinos are critically endangered.
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